MSC Second year : Semester 1: Molecular biology
Credit 1: Genomics 1 mark b) Explain an example of SNP in humans. - SNP Definition: A SNP (Single Nucleotide Polymorphism) is a tiny difference in our genetic code, specifically in a single "letter" of our DNA. A Single Nucleotide Polymorphism (SNP) refers to a minor genetic variation in the DNA sequence of individuals, involving the substitution of a single nucleotide (genetic "letter") at a specific location within the genome. This variation can influence traits, disease susceptibilities, and responses to treatments, albeit typically in combination with other genetic and environmental factors. Example SNP: One well-known SNP is called rs1800497. It's like a tiny spelling change in a gene called IL-6. Impact on Immune System: This SNP can affect how much a protein called IL-6 is made. IL-6 helps our body's defense system and how it responds to inflammation (swelling). Health Connection: Depending on our SNP version (CC, CG, or GG), we might have differe...